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One current study from Yale University found that vanillin — an extract of the vanilla bean — transforms into chemical substances called acetals when aerosolized. Those chemical compounds, the researchers stated, could also be especially irritating to the lungs and trigger injury when inhaled. Studies have shown that breathing in aerosolized propylene glycol could contribute to bronchial asthma. And a 2012 case report involved a woman who developed a condition known as exogenous lipoid pneumonia after vaping for about six months.
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